The BLR-06 Hadra MRL is the heaviest portable weapon in the Helghast army, this beastly rocket launcher has three rocket tubes. The rockets can be fired in either a single fire or can be fired all at once. When all three are fired at once, they arc and spread out, causing a large explosion that will kill or injure anyone who isn't in cover around it. This is the deadliest anti-vehicle weapon in Killzone.

The M404 MAW (Medium Anti-tank Weapon) or M404 Missile Launcher fires single missiles in either dumb-fire or laser-guided mode. It is lighter and easier to transport than its Helghast counterpart, and is nicknamed the "Drainpipe" by ISA troops.

The M80 Missile Launcher is the ISA's anti armor rocket launcher, only found in Killzone 2's Multiplayer and is manufactured by ISA. It basically throws a rocket, which activates its thruster shortly after. It is just as powerful as the VC9 Rocket Launcher, but has a scope, instead of iron-sights. It bears a lot of resemblance to the LAARK from Resistance and the real life SMAW in terms of fire design.The M80 has a homing ability: when scoped in, keep your crosshairs on the target until a diamond shape appears, which is your signal to fire. This ability can only be used on machine targets, such as the Sentry Bot and the Drone.

he VC9 Missile Launcher is the Helghast Rocket Launcher and is manufactured by Visari Corporation. It fires rockets from disposable magazine tubes attached to a firing port. Players can carry 3 rockets at any given time, in both the Campaign and Multiplayer. Its common uses include demolishing enemy equipment and armor, and clearing obstacles. The VC9 has a slightly faster reload time than the M80 Rocket Launcher, but lacks the lock-on feature that the M80 has.
In Multiplayer, the VC9 can be used when being the default soldier, or when the Assault badge is selected.